InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CD33

Summary

InnateDB Protein

IDBP-246970.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CD33

Protein Name

CD33 molecule

Synonyms

p67; SIGLEC-3; SIGLEC3;

Species

Homo sapiens

Ensembl Protein

ENSP00000375673

InnateDB Gene

IDBG-65737 (CD33)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.

Experimentally validated
Total	19 [view]
Protein-Protein	19 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005515	protein binding

Biological Process

GO:0007155	cell adhesion
GO:0007165	signal transduction
GO:0007267	cell-cell signaling
GO:0008285	negative regulation of cell proliferation

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0009897	external side of plasma membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
IPR013162 CD80-like, immunoglobulin C2-set

PFAM

PF07686
PF00047
PF08205

PRINTS

PIRSF

SMART

SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P20138