Version 5.4
Homo sapiens Gene: PCF11
Summary
InnateDB Gene IDBG-66264.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCF11
Gene Name PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000165494
Encoded Proteins
IDBP-66266
PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
IDBP-597292
PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
IDBP-583670
PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
IDBP-590507
PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
IDBP-590042
PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
IDBP-806891
PCF11 cleavage and polyadenylation factor subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:83156988-83187451
Strand Forward strand
Band q14.1
Transcripts
ENST00000298281 ENSP00000298281
ENST00000530660 ENSP00000434540
ENST00000530304 ENSP00000431567
ENST00000533018 ENSP00000436806
ENST00000530906 ENSP00000437076
ENST00000528336
ENST00000624931
ENST00000620955 ENSP00000479505
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 12 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006366 transcription from RNA polymerase II promoter
GO:0006369 termination of RNA polymerase II transcription
GO:0006379 mRNA cleavage
GO:0008380 RNA splicing
GO:0010467 gene expression
GO:0031124 mRNA 3'-end processing
Cellular Component
GO:0005654 nucleoplasm
GO:0005849 mRNA cleavage factor complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041328
View Gene Order
ENSBTAG00000015277
Not yet available
Pathways
NETPATH
REACTOME
REACT_1096
Processing of Intronless Pre-mRNAs pathway
REACT_1849
mRNA 3'-end processing pathway
REACT_467
mRNA Splicing - Major Pathway pathway
REACT_125
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_387
Cleavage of Growing Transcript in the Termination Region pathway
REACT_894
RNA Polymerase II Transcription Termination pathway
REACT_1366
RNA Polymerase II Transcription pathway
REACT_1768
Processing of Capped Intronless Pre-mRNA pathway
REACT_1735
mRNA Splicing pathway
REACT_71
Gene Expression pathway
KEGG
hsa03015
mRNA surveillance pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9PQF9
UniProt Splice Variant
Entrez Gene 51585
UniGene Hs.128959 Hs.595343 Hs.603109 Hs.731825
RefSeq NM_015885
HUGO HGNC:30097
OMIM 608876
CCDS CCDS44689
HPRD 10592
IMGT
EMBL AP000873
GenPept
RNA Seq Atlas 51585

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca