Version 5.4
Homo sapiens Protein: PCF11
Summary
InnateDB Protein IDBP-66266.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCF11
Protein Name PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000298281
InnateDB Gene IDBG-66264 (PCF11)
Protein Structure
UniProt Annotation
Function Component of pre-mRNA cleavage complex II.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 12 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006366 transcription from RNA polymerase II promoter
GO:0006369 termination of RNA polymerase II transcription
GO:0006379 mRNA cleavage
GO:0008380 RNA splicing
GO:0010467 gene expression
GO:0031124 mRNA 3'-end processing
Cellular Component
GO:0005654 nucleoplasm
GO:0005849 mRNA cleavage factor complex
Protein Structure and Domains
PDB ID
InterPro IPR006569 CID domain
IPR006903 RNA polymerase II-binding domain
IPR008942 ENTH/VHS
PFAM PF04818
PRINTS
PIRSF
SMART SM00582
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O94913
PhosphoSite PhosphoSite-O94913
TrEMBL E9PKN0
UniProt Splice Variant
Entrez Gene 51585
UniGene Hs.731825
RefSeq NP_056969
HUGO HGNC:30097
OMIM 608876
CCDS CCDS44689
HPRD 10592
IMGT
EMBL AB020631 AF046935 AP000873 BC065384 BC146778 CH471076
GenPept AAC03107 AAH65384 AAI46779 BAA74847 EAW75083

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca