Version 5.4
Homo sapiens Gene: GPRC5C
Summary
InnateDB Gene IDBG-67203.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPRC5C
Gene Name G protein-coupled receptor, family C, group 5, member C
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170412
Encoded Proteins
IDBP-67205
G protein-coupled receptor, family C, group 5, member C
IDBP-245272
G protein-coupled receptor, family C, group 5, member C
IDBP-245274
G protein-coupled receptor, family C, group 5, member C
IDBP-245276
G protein-coupled receptor, family C, group 5, member C
IDBP-761200
IDBP-757684
IDBP-764014
IDBP-760046
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The specific function of this protein is unknown; however, this protein may mediate the cellular effects of retinoic acid on the G protein signal transduction cascade. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:74424851-74451653
Strand Forward strand
Band q25.1
Transcripts
ENST00000342648 ENSP00000340595
ENST00000392629 ENSP00000376405
ENST00000392628 ENSP00000376404
ENST00000392627 ENSP00000376403
ENST00000481232 ENSP00000462147
ENST00000482723
ENST00000577663
ENST00000582873
ENST00000582473 ENSP00000462440
ENST00000582444 ENSP00000463813
ENST00000581590 ENSP00000463090
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005739 mitochondrion
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0043235 receptor complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000051043
View Gene Order
ENSBTAG00000018663
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.446438 Hs.610226
RefSeq NM_018653 NM_022036 XM_005257513
HUGO
OMIM
CCDS CCDS11699 CCDS42378
HPRD 16178
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca