Version 5.4
| Homo sapiens Gene: HTR3D | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-67294.7 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | HTR3D | ||||||||
| Gene Name | 5-hydroxytryptamine (serotonin) receptor 3D, ionotropic | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Gene | ENSG00000186090 | ||||||||
| Encoded Proteins |
5-hydroxytryptamine (serotonin) receptor 3 family member D
5-hydroxytryptamine (serotonin) receptor 3 family member D
5-hydroxytryptamine (serotonin) receptor 3 family member D
5-hydroxytryptamine (serotonin) receptor 3 family member D
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 3:184031544-184039369 | ||||||||
| Strand | Forward strand | ||||||||
| Band | q27.1 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
| No orthologs found for this gene | |||||||||
| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Ligand-gated ion channel transport pathway
Transmembrane transport of small molecules pathway
Ion channel transport pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Hs.448004 | ||||||||
| RefSeq | NM_001145143 NM_001163646 NM_182537 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | CCDS3249 CCDS46966 CCDS54685 | ||||||||
| HPRD | 17121 | ||||||||
| IMGT | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||