Homo sapiens Gene: HTR3C
Summary
InnateDB Gene IDBG-67333.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HTR3C
Gene Name 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000178084
Encoded Proteins
5-hydroxytryptamine (serotonin) receptor 3, family member C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:184053047-184060671
Strand Forward strand
Band q27.1
Transcripts
ENST00000318351 ENSP00000322617
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005230 extracellular ligand-gated ion channel activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0034220 ion transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Ligand-gated ion channel transport pathway
Transmembrane transport of small molecules pathway
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8WXA8
TrEMBL
UniProt Splice Variant
Entrez Gene 170572
UniGene Hs.632579
RefSeq NM_130770
HUGO HGNC:24003
OMIM 610121
CCDS CCDS3250
HPRD
IMGT
EMBL AF459285 BC131799 CH471052
GenPept AAI31800 AAL66182 EAW78305
RNA Seq Atlas 170572