Version 5.4
Homo sapiens Gene: SLC36A4
Summary
InnateDB Gene IDBG-67866.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC36A4
Gene Name solute carrier family 36 (proton/amino acid symporter), member 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000180773
Encoded Proteins
IDBP-67868
solute carrier family 36 (proton/amino acid symporter), member 4
IDBP-586518
solute carrier family 36 (proton/amino acid symporter), member 4
IDBP-590678
solute carrier family 36 (proton/amino acid symporter), member 4
IDBP-584881
solute carrier family 36 (proton/amino acid symporter), member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SLC36A4 belongs to the SLC36 family of amino acid transporters based on sequence similarity with other family members (e.g., SLC36A1; MIM 606561). SLC36 proteins contain about 500 amino acids and have 9 to 11 transmembrane domains. Unlike other SLC36 family members, which are proton-coupled amino acid transporters, SLC36A4 is a high-affinity/low-capacity non-proton-coupled amino acid transporter (Pillai and Meredith, 2011 [PubMed 21097500]).[supplied by OMIM, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:93144171-93197964
Strand Reverse strand
Band q21
Transcripts
ENST00000326402 ENSP00000317382
ENST00000527503
ENST00000529184 ENSP00000436570
ENST00000526735
ENST00000534116 ENSP00000432061
ENST00000524875 ENSP00000434879
ENST00000527743
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0015293 symporter activity
Biological Process
GO:0015808 L-alanine transport
GO:0015824 proline transport
GO:0015827 tryptophan transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000043885
View Gene Order
ENSBTAG00000008530
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.148766 Hs.596383 Hs.623896
RefSeq NM_001286139 NM_152313 XM_006718762 XM_006718763
HUGO
OMIM
CCDS CCDS66202 CCDS8291
HPRD 15379
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca