Version 5.4
Homo sapiens Protein: SLC36A4
Summary
InnateDB Protein IDBP-586518.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC36A4
Protein Name solute carrier family 36 (proton/amino acid symporter), member 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000436570
InnateDB Gene IDBG-67866 (SLC36A4)
Protein Structure
UniProt Annotation
Function Functions as a sodium-independent electroneutral transporter for tryptophan, proline and alanine. Inhibited by sarcosine. {ECO:0000269PubMed:21097500}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0015293 symporter activity
Biological Process
GO:0015808 L-alanine transport
GO:0015824 proline transport
GO:0015827 tryptophan transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR013057 Amino acid transporter, transmembrane
PFAM PF01490
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6YBV0
PhosphoSite PhosphoSite-Q6YBV0
TrEMBL
UniProt Splice Variant
Entrez Gene 120103
UniGene Hs.623896
RefSeq NP_001273068
HUGO HGNC:19660
OMIM 613760
CCDS CCDS66202
HPRD 15379
IMGT
EMBL AJ295983 AK096251 AY162216 BC047374
GenPept AAH47374 AAO11790 BAC04737 CAC82496

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca