Version 5.4
Homo sapiens Gene: PIWIL4
Summary
InnateDB Gene IDBG-68329.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIWIL4
Gene Name piwi-like 4 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000134627
Encoded Proteins
IDBP-68331
piwi-like 4 (Drosophila)
IDBP-382258
piwi-like 4 (Drosophila)
IDBP-596827
piwi-like 4 (Drosophila)
IDBP-590813
piwi-like 4 (Drosophila)
IDBP-596289
piwi-like 4 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:94543840-94621421
Strand Forward strand
Band q21
Transcripts
ENST00000299001 ENSP00000299001
ENST00000446230 ENSP00000413838
ENST00000543336 ENSP00000444575
ENST00000545603 ENSP00000440499
ENST00000537419 ENSP00000439710
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0034584 piRNA binding
Biological Process
GO:0006417 regulation of translation
GO:0007126 meiotic nuclear division
GO:0007275 multicellular organismal development
GO:0007283 spermatogenesis
GO:0030154 cell differentiation
GO:0031047 gene silencing by RNA
GO:0034587 piRNA metabolic process
GO:0043046 DNA methylation involved in gamete generation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0043186 P granule
GO:0071547 piP-body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036912
View Gene Order
ENSBTAG00000014910
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04320
Dorso-ventral axis formation pathway
INOH
PID NCI
Cross-References
SwissProt Q7Z3Z4
TrEMBL F5GX26
UniProt Splice Variant
Entrez Gene 143689
UniGene Hs.660188
RefSeq NM_152431
HUGO HGNC:18444
OMIM 610315
CCDS CCDS31656
HPRD 11435
IMGT
EMBL AB079366 AK093475 AK096837 AK293616 AP000943 BC031060 CR749642
GenPept AAH31060 BAC04179 BAC04873 BAC81341 BAG57076 CAH18436
RNA Seq Atlas 143689

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca