Version 5.4
| Homo sapiens Gene: LILRA5 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-68498.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | LILRA5 | ||||||||||
| Gene Name | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 | ||||||||||
| Synonyms | |||||||||||
| Species | Homo sapiens | ||||||||||
| Ensembl Gene | ENSG00000187116 | ||||||||||
| Encoded Proteins |
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
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| Protein Structure | |||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 19:54307070-54313139 | ||||||||||
| Strand | Reverse strand | ||||||||||
| Band | q13.42 | ||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
| No orthologs found for this gene | |||||||||||
| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME | |||||||||||
| KEGG |
Osteoclast differentiation pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | |||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | |||||||||||
| UniGene | Hs.710986 | ||||||||||
| RefSeq | NM_021250 NM_181985 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | CCDS12888 CCDS12889 | ||||||||||
| HPRD | 06924 | ||||||||||
| IMGT | |||||||||||
| EMBL | |||||||||||
| GenPept | |||||||||||
| RNA Seq Atlas | |||||||||||