Version 5.4
Homo sapiens Gene: PPP1R3B
Summary
InnateDB Gene IDBG-6897.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R3B
Gene Name protein phosphatase 1, regulatory subunit 3B
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000173281
Encoded Proteins
IDBP-6899
protein phosphatase 1, regulatory subunit 3B
IDBP-485381
protein phosphatase 1, regulatory subunit 3B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes the catalytic subunit of the serine/theonine phosphatase, protein phosphatase-1. The encoded protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:9136255-9151574
Strand Reverse strand
Band p23.1
Transcripts
ENST00000310455 ENSP00000308318
ENST00000519699 ENSP00000428642
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004721 phosphoprotein phosphatase activity
GO:0005515 protein binding
GO:0019888 protein phosphatase regulator activity
GO:0019899 enzyme binding
Biological Process
GO:0005977 glycogen metabolic process
GO:0005979 regulation of glycogen biosynthetic process
GO:0005981 regulation of glycogen catabolic process
GO:0016311 dephosphorylation
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0000164 protein phosphatase type 1 complex
GO:0042587 glycogen granule
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000046794
View Gene Order
ENSBTAG00000010606
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04910
Insulin signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt Q86XI6
TrEMBL
UniProt Splice Variant
Entrez Gene 79660
UniGene Hs.458513 Hs.743934
RefSeq NM_001201329 NM_024607 XM_006716253 XM_006716254
HUGO HGNC:14942
OMIM 610541
CCDS CCDS5973
HPRD
IMGT
EMBL AK024067 AK096119 BC043388 CH471157
GenPept AAH43388 BAB14811 BAG53215 EAW65572
RNA Seq Atlas 79660

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca