Version 5.4
Homo sapiens Gene: RDH13
Summary
InnateDB Gene IDBG-69990.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RDH13
Gene Name retinol dehydrogenase 13 (all-trans/9-cis)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000160439
Encoded Proteins
IDBP-69992
retinol dehydrogenase 13 (all-trans/9-cis)
IDBP-237901
retinol dehydrogenase 13 (all-trans/9-cis)
IDBP-385239
retinol dehydrogenase 13 (all-trans/9-cis)
IDBP-765002
IDBP-762025
IDBP-761610
IDBP-763867
IDBP-766140
IDBP-812696
retinol dehydrogenase 13 (all-trans/9-cis)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation of retinoids. The encoded enzyme may function in retinoic acid production and may also protect the mitochondria against oxidative stress. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:55039108-55071291
Strand Reverse strand
Band q13.42
Transcripts
ENST00000291892 ENSP00000291892
ENST00000396247 ENSP00000379547
ENST00000415061 ENSP00000391121
ENST00000591023
ENST00000592423
ENST00000591960 ENSP00000468422
ENST00000588306
ENST00000591603
ENST00000593134
ENST00000587721 ENSP00000467208
ENST00000588941
ENST00000589605
ENST00000589305
ENST00000587046
ENST00000586945 ENSP00000466708
ENST00000590349
ENST00000587373
ENST00000592573 ENSP00000465538
ENST00000589197
ENST00000587026 ENSP00000467754
ENST00000586331
ENST00000610356 ENSP00000477732
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0050662 coenzyme binding
Biological Process
GO:0008152 metabolic process
GO:0009644 response to high light intensity
GO:0010842 retina layer formation
GO:0042462 eye photoreceptor cell development
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000008435
View Gene Order
ENSBTAG00000030393
Not yet available
Cross-References
SwissProt
TrEMBL K7ERV1
UniProt Splice Variant
Entrez Gene 112724
UniGene Hs.327631 Hs.601399 Hs.690951 Hs.731615
RefSeq NM_001145971 NM_138412 XM_005258473 XM_005277093 XM_005277199 XM_005277238 XM_005277295 XM_006725861 XM_006725949 XM_006726048 XM_006726146 XM_006726184
HUGO HGNC:19978
OMIM
CCDS CCDS42627 CCDS54320
HPRD 17963
IMGT
EMBL AC011476
GenPept
RNA Seq Atlas 102724045 112724

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca