InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: H1F0

Summary

InnateDB Gene

IDBG-7017.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

H1F0

Gene Name

H1 histone family, member 0

Synonyms

H10; H1FV

Species

Homo sapiens

Ensembl Gene

ENSG00000189060

Encoded Proteins

IDBP-7019

H1 histone family, member 0

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 22:37805093-37807436

Strand

Forward strand

Band

q13.1

Transcripts

ENST00000340857

ENSP00000344504

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	32 [view]
Protein-Protein	32 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding
GO:0031490	chromatin DNA binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006309	apoptotic DNA fragmentation
GO:0006334	nucleosome assembly
GO:0006915	apoptotic process
GO:0006921	cellular component disassembly involved in execution phase of apoptosis

Cellular Component

GO:0000786	nucleosome
GO:0000790	nuclear chromatin
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005719	nuclear euchromatin
GO:0005794	Golgi apparatus
GO:0015629	actin cytoskeleton