InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: RBM4

Summary

InnateDB Gene

IDBG-702473.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RBM4

Gene Name

RNA-binding protein 4

Synonyms

1300007E16Rik; 4921506I22Rik; lark; Lark1; Mlark; p16; p16K; PSP2; Rbm4a; Sytip

Species

Mus musculus

Ensembl Gene

ENSMUSG00000096370

Encoded Proteins

IDBP-619833

RNA binding motif protein 14

IDBP-704366

IDBP-705380

IDBP-704315

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000248643:
This locus represents naturally occurring read-through transcription between the neighboring RBM14 (RNA binding motif protein 14) and RBM4 (RNA binding motif protein 4) genes. Alternative splicing results in multiple transcript variants, one of which encodes a fusion protein that shares sequence identity with each individual gene product. This fusion protein contains RRM and zinc finger domains, and it functions to stimulate transcription in a hormone and receptor-dependent manner. [provided by RefSeq, Nov 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:4742913-4811612

Strand

Reverse strand

Band

Transcripts

ENSMUST00000172000	ENSMUSP00000128810
ENSMUST00000179909	ENSMUSP00000136623
ENSMUST00000178404	ENSMUSP00000137562
ENSMUST00000178353	ENSMUSP00000136599
ENSMUST00000177776
ENSMUST00000178727

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 49 interaction(s) predicted by orthology.

Predicted by orthology
Total	49 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0003730	mRNA 3'-UTR binding
GO:0008270	zinc ion binding
GO:0035198	miRNA binding
GO:0036002	pre-mRNA binding
GO:0097157	pre-mRNA intronic binding
GO:0097158	pre-mRNA intronic pyrimidine-rich binding

Biological Process

GO:0000381	regulation of alternative mRNA splicing, via spliceosome
GO:0002190	cap-independent translational initiation
GO:0002192	IRES-dependent translational initiation
GO:0006397	mRNA processing
GO:0008380	RNA splicing
GO:0017148	negative regulation of translation
GO:0030154	cell differentiation
GO:0032055	negative regulation of translation in response to stress
GO:0035278	negative regulation of translation involved in gene silencing by miRNA
GO:0043153	entrainment of circadian clock by photoperiod
GO:0045947	negative regulation of translational initiation
GO:0046685	response to arsenic-containing substance
GO:0046822	regulation of nucleocytoplasmic transport
GO:0051149	positive regulation of muscle cell differentiation
GO:0051403	stress-activated MAPK cascade
GO:0097167	circadian regulation of translation

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0010494	cytoplasmic stress granule
GO:0016607	nuclear speck
GO:0048471	perinuclear region of cytoplasm

Orthologs

Species

Homo sapiens

Gene ID

Gene Order

ENSG00000248643

View Gene Order

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.447455

RefSeq

OMIM

CCDS

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas