Version 5.4
Mus musculus Gene: ENTPD4
Summary
InnateDB Gene IDBG-703704.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ENTPD4
Gene Name Ectonucleoside triphosphate diphosphohydrolase 4
Synonyms 1200014F22Rik; 4930513O14Rik; A430102M06Rik; AI414893; Lysal1; mKIAA0392
Species Mus musculus
Ensembl Gene ENSMUSG00000095463
Encoded Proteins
IDBP-177231
ectonucleoside triphosphate diphosphohydrolase 4
IDBP-789402
ectonucleoside triphosphate diphosphohydrolase 4
IDBP-789403
ectonucleoside triphosphate diphosphohydrolase 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000197217:
This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:69337174-69367270
Strand Forward strand
Band D2
Transcripts
ENSMUST00000064831 ENSMUSP00000065046
ENSMUST00000184973 ENSMUSP00000138944
ENSMUST00000184165
ENSMUST00000184314 ENSMUSP00000138892
ENSMUST00000183648
ENSMUST00000184234
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0045134 uridine-diphosphatase activity
Biological Process
GO:0006256 UDP catabolic process
GO:0008152 metabolic process
Cellular Component
GO:0000139 Golgi membrane
GO:0000421 autophagic vacuole membrane
GO:0016021 integral component of membrane
GO:0030173 integral component of Golgi membrane
GO:0031410 cytoplasmic vesicle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000197217
View Gene Order
ENSBTAG00000006768
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00240
Pyrimidine metabolism pathway
mmu00230
Purine metabolism pathway
mmu04142
Lysosome pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
hsa04142
Lysosome pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
INOH website
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_026174 XM_003688928
OMIM
CCDS CCDS27240
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca