InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Hmgcs1

Summary

InnateDB Gene

IDBG-704205.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hmgcs1

Gene Name

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000093930

Encoded Proteins

IDBP-714046

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112972:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:119690462-119708086

Strand

Forward strand

Band

D2.3

Transcripts

ENSMUST00000179869

ENSMUSP00000136944

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004421	hydroxymethylglutaryl-CoA synthase activity
GO:0008144	drug binding
GO:0016853	isomerase activity
GO:0042803	protein homodimerization activity
GO:0043177	organic acid binding

Biological Process

GO:0001101	response to acid
GO:0001889	liver development
GO:0006695	cholesterol biosynthetic process
GO:0007420	brain development
GO:0008152	metabolic process
GO:0008299	isoprenoid biosynthetic process
GO:0008584	male gonad development
GO:0009645	response to low light intensity stimulus
GO:0009725	response to hormone
GO:0010033	response to organic substance
GO:0010243	response to organonitrogen compound
GO:0014070	response to organic cyclic compound
GO:0014074	response to purine-containing compound
GO:0033197	response to vitamin E
GO:0034698	response to gonadotropin
GO:0042493	response to drug
GO:0046690	response to tellurium ion
GO:0055094	response to lipoprotein particle stimulus
GO:0070723	response to cholesterol
GO:0071372	cellular response to follicle-stimulating hormone stimulus
GO:0071397	cellular response to cholesterol
GO:0071407	cellular response to organic cyclic compound