InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: GALR3

Summary

InnateDB Gene

IDBG-7050.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GALR3

Gene Name

galanin receptor 3

Synonyms

Species

Homo sapiens

Ensembl Gene

ENSG00000128310

Encoded Proteins

IDBP-7052

galanin receptor 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts [provided by RefSeq, Jul 2008]
The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 22:37823382-37825495

Strand

Forward strand

Band

q13.1

Transcripts

ENST00000249041

ENSP00000249041

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004966	galanin receptor activity
GO:0017046	peptide hormone binding

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007194	negative regulation of adenylate cyclase activity
GO:0007218	neuropeptide signaling pathway
GO:0007268	synaptic transmission
GO:0007611	learning or memory
GO:0007631	feeding behavior
GO:0030818	negative regulation of cAMP biosynthetic process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter