InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GALR3

Summary

InnateDB Protein

IDBP-7052.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GALR3

Protein Name

galanin receptor 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000249041

InnateDB Gene

IDBG-7050 (GALR3)

Protein Structure

UniProt Annotation

Function

Receptor for the hormone galanin. Receptor for the hormone spexin-1 (PubMed:24517231). {ECO:0000269PubMed:24517231}.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0004966	galanin receptor activity
GO:0017046	peptide hormone binding

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007194	negative regulation of adenylate cyclase activity
GO:0007218	neuropeptide signaling pathway
GO:0007268	synaptic transmission
GO:0007611	learning or memory
GO:0007631	feeding behavior
GO:0030818	negative regulation of cAMP biosynthetic process
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005886	plasma membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000405 Galanin receptor family
IPR003908 Galanin receptor 3
IPR017452 GPCR, rhodopsin-like, 7TM

PFAM

PF00001

PRINTS

PR00237
PR00663
PR01420

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O60755