Version 5.4
Homo sapiens Gene: ACAP2
Summary
InnateDB Gene IDBG-70506.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACAP2
Gene Name ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
Synonyms CENTB2; CNT-B2
Species Homo sapiens
Ensembl Gene ENSG00000114331
Encoded Proteins
IDBP-70508
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
IDBP-386842
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
IDBP-386844
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
IDBP-386845
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
IDBP-386846
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
IDBP-386847
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
IDBP-807043
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:195274736-195443078
Strand Reverse strand
Band q29
Transcripts
ENST00000326793 ENSP00000324287
ENST00000450200 ENSP00000412338
ENST00000439758 ENSP00000413388
ENST00000423531 ENSP00000399855
ENST00000439666 ENSP00000411336
ENST00000447662 ENSP00000405262
ENST00000472860
ENST00000466876
ENST00000475905
ENST00000484296
ENST00000471593
ENST00000480906
ENST00000481463
ENST00000490224
ENST00000618471 ENSP00000484209
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
GO:0017137 Rab GTPase binding
Biological Process
GO:0032312 regulation of ARF GTPase activity
GO:0036010 protein localization to endosome
GO:0043547 positive regulation of GTPase activity
GO:1990090 cellular response to nerve growth factor stimulus
Cellular Component
GO:0010008 endosome membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000049076
View Gene Order
ENSBTAG00000003378
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
arf6_pathway
Arf6 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.593373 Hs.631077 Hs.704672 Hs.733132
RefSeq NM_012287 XM_006713557 XM_006713558
HUGO
OMIM
CCDS CCDS33924
HPRD 09681
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca