Version 5.4
Mus musculus Gene: Acap2
Summary
InnateDB Gene IDBG-152700.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Acap2
Gene Name ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
Synonyms 4832442G16; 9530039J15Rik; Centb2; CNT-B2; mKIAA0041
Species Mus musculus
Ensembl Gene ENSMUSG00000049076
Encoded Proteins
IDBP-152702
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114331:
Gene Information
Type Protein coding
Genomic Location Chromosome 16:31092413-31201238
Strand Reverse strand
Band B2
Transcripts
ENSMUST00000058033 ENSMUSP00000061501
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
GO:0017137 Rab GTPase binding
Biological Process
GO:0032312 regulation of ARF GTPase activity
GO:0036010 protein localization to endosome
GO:0043547 positive regulation of GTPase activity
GO:1990090 cellular response to nerve growth factor stimulus
Cellular Component
GO:0010008 endosome membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000114331
View Gene Order
ENSBTAG00000003378
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04144
Endocytosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
arf6_pathway
Arf6 signaling events
Cross-References
SwissProt Q6ZQK5
TrEMBL D4AFX6
UniProt Splice Variant
Entrez Gene 78618
UniGene Mm.274646 Mm.398869 Mm.407403
RefSeq NM_030138 XM_006522748 XM_006522749
OMIM
CCDS CCDS49823
HPRD
IMGT
MGI ID MGI:1925868
MGI Symbol Acap2
EMBL AB490692 AK020591 AK129041 AK147319 BC046455
GenPept AAH46455 BAB32141 BAC97851 BAE27843 BAI82352
RNA Seq Atlas 78618

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca