Version 5.4
Mus musculus Gene: TAF1A
Summary
InnateDB Gene IDBG-705697.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAF1A
Gene Name TATA box-binding protein-associated factor RNA polymerase I subunit A
Synonyms mTAFI48; TAFI48
Species Mus musculus
Ensembl Gene ENSMUSG00000072258
Encoded Proteins
IDBP-715306
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143498:
This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.[provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:183388981-183409353
Strand Forward strand
Band H5
Transcripts
ENSMUST00000097043 ENSMUSP00000094808
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006360 transcription from RNA polymerase I promoter
Cellular Component
GO:0000120 RNA polymerase I transcription factor complex
GO:0005634 nucleus
GO:0015630 microtubule cytoskeleton
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143498
View Gene Order
ENSBTAG00000013483
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1074
RNA Polymerase I Transcription Termination pathway
REACT_2204
RNA Polymerase I Chain Elongation pathway
REACT_1913
RNA Polymerase I Promoter Escape pathway
REACT_953
RNA Polymerase I Transcription Initiation pathway
REACT_1309
RNA Polymerase I Transcription pathway
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_1974
RNA Polymerase I Promoter Clearance pathway
REACT_200856
NoRC negatively regulates rRNA expression pathway
REACT_200827
SIRT1 negatively regulates rRNA Expression pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_71
Gene Expression pathway
REACT_200834
Negative epigenetic regulation of rRNA expression pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL J3KMG9
UniProt Splice Variant
Entrez Gene 21339
UniGene Mm.383556
RefSeq NM_001277958 NM_001277959 NM_021466
OMIM
CCDS
HPRD
IMGT
MGI ID MGI:109578
MGI Symbol Taf1a
EMBL CAAA01083515 CAAA01083517 CAAA01117637
GenPept
RNA Seq Atlas 21339

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca