Version 5.4
Homo sapiens Gene: USP36
Summary
InnateDB Gene IDBG-70923.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol USP36
Gene Name ubiquitin specific peptidase 36
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000055483
Encoded Proteins
IDBP-70925
ubiquitin specific peptidase 36
IDBP-385102
ubiquitin specific peptidase 36
IDBP-591809
ubiquitin specific peptidase 36
IDBP-761127
IDBP-760979
IDBP-758307
IDBP-759923
IDBP-758601
IDBP-764048
IDBP-810293
ubiquitin specific peptidase 36
IDBP-764741
IDBP-763826
IDBP-759042
IDBP-762434
IDBP-764811
IDBP-763821
IDBP-760203
IDBP-760572
IDBP-759554
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP36 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:78787381-78841441
Strand Reverse strand
Band q25.3
Transcripts
ENST00000312010 ENSP00000310590
ENST00000449938 ENSP00000401119
ENST00000542802 ENSP00000441214
ENST00000590312
ENST00000587783 ENSP00000468194
ENST00000592326
ENST00000592231 ENSP00000465698
ENST00000589424 ENSP00000466187
ENST00000588467
ENST00000588365 ENSP00000465183
ENST00000589254
ENST00000592907
ENST00000587010 ENSP00000465679
ENST00000586896 ENSP00000467951
ENST00000591942 ENSP00000475654
ENST00000588086 ENSP00000468549
ENST00000588130 ENSP00000464746
ENST00000587379 ENSP00000464886
ENST00000589225 ENSP00000467280
ENST00000590546 ENSP00000467682
ENST00000591052 ENSP00000468356
ENST00000592275 ENSP00000466212
ENST00000586531 ENSP00000467520
ENST00000586066 ENSP00000466567
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
Experimentally validated
Total 29 [view]
Protein-Protein 28 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
GO:0036459 ubiquitinyl hydrolase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016579 protein deubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033909
View Gene Order
ENSBTAG00000021505
Not yet available
Cross-References
SwissProt
TrEMBL K7EJI3 K7ELT3 K7EPT1 K7EQS0 K7ERC1 Q8IXW9
UniProt Splice Variant
Entrez Gene 57602
UniGene Hs.464243 Hs.603540 Hs.626718
RefSeq NM_025090 XM_005257542 XM_005257543 XM_005257544
HUGO HGNC:20062
OMIM 612543
CCDS CCDS32755
HPRD 07164
IMGT
EMBL AC022966 BC038983
GenPept AAH38983
RNA Seq Atlas 57602

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca