Version 5.4
Homo sapiens Gene: SLC26A11
Summary
InnateDB Gene IDBG-71590.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC26A11
Gene Name solute carrier family 26, member 11
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000181045
Encoded Proteins
IDBP-71592
solute carrier family 26, member 11
IDBP-385197
solute carrier family 26, member 11
IDBP-585825
solute carrier family 26, member 11
IDBP-762494
IDBP-760044
IDBP-759932
IDBP-761348
IDBP-762870
IDBP-759296
IDBP-759915
IDBP-761174
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the solute linked carrier 26 family of anion exchangers. Members of this family of proteins are essential for numerous cellular functions including homeostasis and intracellular electrolyte balance. The encoded protein is a sodium independent sulfate transporter that is sensitive to the anion exchanger inhibitor 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:80219699-80253500
Strand Forward strand
Band q25.3
Transcripts
ENST00000361193 ENSP00000355384
ENST00000411502 ENSP00000403998
ENST00000546047 ENSP00000440724
ENST00000571176 ENSP00000458831
ENST00000576126 ENSP00000459420
ENST00000571072
ENST00000571888
ENST00000573809 ENSP00000459735
ENST00000574967 ENSP00000460535
ENST00000571564
ENST00000571215 ENSP00000458234
ENST00000577155 ENSP00000458521
ENST00000572652
ENST00000571602
ENST00000575019 ENSP00000459379
ENST00000572725 ENSP00000459470
ENST00000572226
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008271 secondary active sulfate transmembrane transporter activity
GO:0008509 anion transmembrane transporter activity
GO:0015116 sulfate transmembrane transporter activity
GO:0015301 anion:anion antiporter activity
Biological Process
GO:0008272 sulfate transport
GO:1902358 sulfate transmembrane transport
Cellular Component
GO:0005765 lysosomal membrane
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039908
View Gene Order
ENSBTAG00000015276
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.4866
RefSeq NM_001166347 NM_001166348 NM_001166349 NM_173626
HUGO
OMIM
CCDS CCDS11771
HPRD 11569
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca