Version 5.4
Homo sapiens Gene: NPTX1
Summary
InnateDB Gene IDBG-71788.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NPTX1
Gene Name neuronal pentraxin I
Synonyms NP1
Species Homo sapiens
Ensembl Gene ENSG00000171246
Encoded Proteins
IDBP-71790
neuronal pentraxin I
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:80467148-80477843
Strand Reverse strand
Band q25.3
Transcripts
ENST00000306773 ENSP00000307549
ENST00000535681
ENST00000575212
ENST00000571100
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0006810 transport
GO:0006839 mitochondrial transport
GO:0007268 synaptic transmission
GO:0007417 central nervous system development
GO:0035865 cellular response to potassium ion
GO:0043653 mitochondrial fragmentation involved in apoptotic process
GO:0060385 axonogenesis involved in innervation
GO:0071333 cellular response to glucose stimulus
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005886 plasma membrane
GO:0030133 transport vesicle
GO:0043005 neuron projection
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000025582
View Gene Order
ENSBTAG00000008940
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.743812
RefSeq NM_002522
HUGO
OMIM
CCDS CCDS32762
HPRD 03843
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca