InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NPTX1

Summary

InnateDB Protein

IDBP-71790.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NPTX1

Protein Name

neuronal pentraxin I

Synonyms

NP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000307549

InnateDB Gene

IDBG-71788 (NPTX1)

Protein Structure

UniProt Annotation

Function

May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses. {ECO:0000250}.

Subcellular Localization

Cytoplasmic vesicle, secretory vesicle {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0046872	metal ion binding

Biological Process

GO:0006810	transport
GO:0006839	mitochondrial transport
GO:0007268	synaptic transmission
GO:0007417	central nervous system development
GO:0035865	cellular response to potassium ion
GO:0043653	mitochondrial fragmentation involved in apoptotic process
GO:0060385	axonogenesis involved in innervation
GO:0071333	cellular response to glucose stimulus