Version 5.4
Homo sapiens Gene: PGBD1
Summary
InnateDB Gene IDBG-71884.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PGBD1
Gene Name piggyBac transposable element derived 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137338
Encoded Proteins
IDBP-71886
piggyBac transposable element derived 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene product is specifically expressed in the brain, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:28281572-28302549
Strand Forward strand
Band p22.1
Transcripts
ENST00000259883 ENSP00000259883
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005044 scavenger receptor activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006898 receptor-mediated endocytosis
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000055313
View Gene Order
ENSBTAG00000046573
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.144527
RefSeq NM_001184743 NM_032507 XM_006715228
HUGO
OMIM
CCDS CCDS4648
HPRD 11426
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca