Version 5.4
| Homo sapiens Gene: DLGAP4 | |||||||||||||||||||||||
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| Summary | |||||||||||||||||||||||
| InnateDB Gene | IDBG-72439.6 | ||||||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
| Gene Symbol | DLGAP4 | ||||||||||||||||||||||
| Gene Name | discs, large (Drosophila) homolog-associated protein 4 | ||||||||||||||||||||||
| Synonyms | DAP-4; DAP4; DLP4; SAPAP-4; SAPAP4 | ||||||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||||||
| Ensembl Gene | ENSG00000080845 | ||||||||||||||||||||||
| Encoded Proteins |
discs, large (Drosophila) homolog-associated protein 4
discs, large (Drosophila) homolog-associated protein 4
discs, large (Drosophila) homolog-associated protein 4
discs, large (Drosophila) homolog-associated protein 4
discs, large (Drosophila) homolog-associated protein 4
discs, large (Drosophila) homolog-associated protein 4
discs, large (Drosophila) homolog-associated protein 4
discs, large (Drosophila) homolog-associated protein 4
discs, large (Drosophila) homolog-associated protein 4
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
| Entrez Gene | |||||||||||||||||||||||
| Summary |
The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||||||
| Genomic Location | Chromosome 20:36306336-36528637 | ||||||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||||||
| Band | q11.23 | ||||||||||||||||||||||
| Transcripts | |||||||||||||||||||||||
| Interactions | |||||||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||||||||||||||||
| SwissProt | Q9Y2H0 | ||||||||||||||||||||||
| TrEMBL | |||||||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||||||
| Entrez Gene | 22839 | ||||||||||||||||||||||
| UniGene | Hs.249600 Hs.661168 | ||||||||||||||||||||||
| RefSeq | NM_183006 NM_001042486 NM_014902 XM_005260329 XM_005260332 | ||||||||||||||||||||||
| HUGO | HGNC:24476 | ||||||||||||||||||||||
| OMIM | |||||||||||||||||||||||
| CCDS | CCDS13275 CCDS13274 | ||||||||||||||||||||||
| HPRD | 16826 | ||||||||||||||||||||||
| IMGT | |||||||||||||||||||||||
| EMBL | AB023181 AL050318 AL390374 BC108706 BC153874 CH471077 | ||||||||||||||||||||||
| GenPept | AAI08707 AAI53875 BAA76808 CAI17927 CAI17928 CAI17929 CAI23506 CAI23507 CAI23509 EAW76135 EAW76136 EAW76140 | ||||||||||||||||||||||
| RNA Seq Atlas | 22839 | ||||||||||||||||||||||