Version 5.4
Homo sapiens Protein: DLGAP4
Summary
InnateDB Protein IDBP-72441.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DLGAP4
Protein Name discs, large (Drosophila) homolog-associated protein 4
Synonyms DAP-4; DAP4; DLP4; SAPAP-4; SAPAP4;
Species Homo sapiens
Ensembl Protein ENSP00000363023
InnateDB Gene IDBG-72439 (DLGAP4)
Protein Structure
UniProt Annotation
Function May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane.
Subcellular Localization Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007267 cell-cell signaling
Cellular Component
GO:0016020 membrane
GO:0045202 synapse
Protein Structure and Domains
PDB ID
InterPro IPR005026 Guanylate-kinase-associated protein
PFAM PF03359
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y2H0
PhosphoSite PhosphoSite-Q9Y2H0
TrEMBL
UniProt Splice Variant
Entrez Gene 22839
UniGene Hs.661168
RefSeq XP_005260388
HUGO HGNC:24476
OMIM
CCDS CCDS13274
HPRD 16826
IMGT
EMBL AB023181 AL050318 AL390374 BC108706 BC153874 CH471077
GenPept AAI08707 AAI53875 BAA76808 CAI17927 CAI17928 CAI17929 CAI23506 CAI23507 CAI23509 EAW76135 EAW76136 EAW76140

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca