Version 5.4
Homo sapiens Gene: ZSCAN4
Summary
InnateDB Gene IDBG-72512.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZSCAN4
Gene Name zinc finger and SCAN domain containing 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000180532
Encoded Proteins
IDBP-72514
zinc finger and SCAN domain containing 4
IDBP-806666
zinc finger and SCAN domain containing 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The ZSCAN4 gene encodes a protein involved in telomere maintenance and with a key role in the critical feature of mouse embryonic stem (ES) cells, namely, defying cellular senescence and maintaining normal karyotype for many cell divisions in culture (Zalzman et al., 2010 [PubMed 20336070]).[supplied by OMIM, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:57668935-57679152
Strand Forward strand
Band q13.43
Transcripts
ENST00000318203 ENSP00000321963
ENST00000612521 ENSP00000480210
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0010833 telomere maintenance via telomere lengthening
Cellular Component
GO:0000784 nuclear chromosome, telomeric region
GO:0005634 nucleus
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.469663
RefSeq NM_152677 XM_006723078
HUGO
OMIM
CCDS CCDS12958
HPRD 15899
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca