Version 5.4
Homo sapiens Gene: MYH4
Summary
InnateDB Gene IDBG-729182.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYH4
Gene Name myosin, heavy chain 4, skeletal muscle
Synonyms MYH2B; MyHC-2B; MyHC-IIb
Species Homo sapiens
Ensembl Gene ENSG00000264424
Encoded Proteins
IDBP-30265
myosin, heavy chain 4, skeletal muscle
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:10443290-10469559
Strand Reverse strand
Band p13.1
Transcripts
ENST00000255381 ENSP00000255381
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000146 microfilament motor activity
GO:0000166 nucleotide binding
GO:0003725 double-stranded RNA binding
GO:0003774 motor activity
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
Biological Process
GO:0006200 ATP catabolic process
GO:0006936 muscle contraction
GO:0014823 response to activity
GO:0030048 actin filament-based movement
GO:0030049 muscle filament sliding
GO:0061024 membrane organization
Cellular Component
GO:0005859 muscle myosin complex
GO:0016459 myosin complex
GO:0030016 myofibril
GO:0030017 sarcomere
GO:0032982 myosin filament
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000057003
View Gene Order
ENSBTAG00000037794
Not yet available
Pathways
NETPATH
REACTOME
REACT_147867
Translocation of GLUT4 to the plasma membrane pathway
REACT_11123
Membrane Trafficking pathway
KEGG
hsa04530
Tight junction pathway
INOH
PID NCI
Cross-References
SwissProt Q9Y623
TrEMBL
UniProt Splice Variant
Entrez Gene 4622
UniGene Hs.711141
RefSeq NM_017533 XM_005256650
HUGO HGNC:7574
OMIM 160742
CCDS CCDS11154
HPRD
IMGT
EMBL AC005323 AF111783
GenPept AAD29949
RNA Seq Atlas 4622

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca