Version 5.4
Homo sapiens Gene: TMPRSS13
Summary
InnateDB Gene IDBG-73366.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMPRSS13
Gene Name transmembrane protease, serine 13
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000137747
Encoded Proteins
IDBP-383578
transmembrane protease, serine 13
IDBP-383579
transmembrane protease, serine 13
IDBP-600164
transmembrane protease, serine 13
IDBP-600188
transmembrane protease, serine 13
IDBP-603506
transmembrane protease, serine 13
IDBP-585330
transmembrane protease, serine 13
IDBP-807698
transmembrane protease, serine 13
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the type II transmembrane serine protease family. Transmembrane serine proteases are regulated by protease inhibitors and known to function in development, homeostasis, infection, and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:117900643-117929459
Strand Reverse strand
Band q23.3
Transcripts
ENST00000445164 ENSP00000394114
ENST00000430170 ENSP00000387702
ENST00000528626 ENSP00000435813
ENST00000524993 ENSP00000434279
ENST00000526090 ENSP00000436502
ENST00000528135 ENSP00000436025
ENST00000525794
ENST00000614424 ENSP00000480143
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
GO:0070008 serine-type exopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006898 receptor-mediated endocytosis
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0072562 blood microparticle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037129
View Gene Order
ENSBTAG00000008342
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001077263 NM_001206789 NM_001206790 NM_001244995
HUGO
OMIM
CCDS CCDS41721 CCDS55788 CCDS55789 CCDS58185
HPRD 07493
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca