Version 5.4
Homo sapiens Gene: RBMS1
Summary
InnateDB Gene IDBG-73446.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBMS1
Gene Name RNA binding motif, single stranded interacting protein 1
Synonyms C2orf12; HCC-4; MSSP; MSSP-1; MSSP-2; MSSP-3; SCR2; YC1
Species Homo sapiens
Ensembl Gene ENSG00000153250
Encoded Proteins
IDBP-73450
RNA binding motif, single stranded interacting protein 1
IDBP-244996
RNA binding motif, single stranded interacting protein 1
IDBP-293898
RNA binding motif, single stranded interacting protein 1
IDBP-293890
RNA binding motif, single stranded interacting protein 1
IDBP-293896
RNA binding motif, single stranded interacting protein 1
IDBP-386896
RNA binding motif, single stranded interacting protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:160272151-160493794
Strand Reverse strand
Band q24.2
Transcripts
ENST00000348849 ENSP00000294904
ENST00000392753 ENSP00000376508
ENST00000409075 ENSP00000386347
ENST00000409289 ENSP00000386571
ENST00000409972 ENSP00000387280
ENST00000428519 ENSP00000389016
ENST00000474820
ENST00000474147
ENST00000475103
ENST00000490637
ENST00000477965
ENST00000464200
ENST00000491781
ENST00000492283
ENST00000477486
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 30 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006260 DNA replication
GO:0006396 RNA processing
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026970
View Gene Order
ENSBTAG00000005180
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.470412 Hs.600749 Hs.654231 Hs.708357
RefSeq NM_002897 NM_016836 XM_006712673 XM_006712674
HUGO
OMIM
CCDS CCDS2213
HPRD 03814
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca