Version 5.4
Homo sapiens Protein: RBMS1
Summary
InnateDB Protein IDBP-73450.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBMS1
Protein Name RNA binding motif, single stranded interacting protein 1
Synonyms C2orf12; HCC-4; MSSP; MSSP-1; MSSP-2; MSSP-3; SCR2; YC1;
Species Homo sapiens
Ensembl Protein ENSP00000294904
InnateDB Gene IDBG-73446 (RBMS1)
Protein Structure
UniProt Annotation
Function Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity Highest amounts are found in placenta, lung and heart.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 30 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006260 DNA replication
GO:0006396 RNA processing
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR002343 Paraneoplastic encephalomyelitis antigen
PFAM PF00076
PRINTS PR00961
PIRSF
SMART SM00360
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P29558
PhosphoSite PhosphoSite-P29558
TrEMBL Q9UEK5
UniProt Splice Variant
Entrez Gene 5937
UniGene Hs.708357
RefSeq NP_058520
HUGO HGNC:9907
OMIM 602310
CCDS CCDS2213
HPRD 03814
IMGT
EMBL AC092153 AC104598 AC131754 AC133105 BC012992 BC012993 BC018951 D28482 D82361 X64652 X77494
GenPept AAH12992 AAH12993 AAH18951 AAX93095 AAX93183 AAY15005 BAA05841 BAA20858 CAA45923 CAA54628

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca