Version 5.4
Homo sapiens Gene: UTS2R
Summary
InnateDB Gene IDBG-73504.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UTS2R
Gene Name urotensin 2 receptor
Synonyms GPR14; UR-2-R; UTR; UTR2
Species Homo sapiens
Ensembl Gene ENSG00000181408
Encoded Proteins
IDBP-73506
urotensin 2 receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:82374230-82375586
Strand Forward strand
Band q25.3
Transcripts
ENST00000313135 ENSP00000323516
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001604 urotensin II receptor activity
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0003105 negative regulation of glomerular filtration
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008015 blood circulation
GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness
GO:0030307 positive regulation of cell growth
GO:0035811 negative regulation of urine volume
GO:0035814 negative regulation of renal sodium excretion
GO:0042312 regulation of vasodilation
GO:0042493 response to drug
GO:0045766 positive regulation of angiogenesis
GO:0045776 negative regulation of blood pressure
GO:0045777 positive regulation of blood pressure
GO:0045907 positive regulation of vasoconstriction
GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep
GO:0048146 positive regulation of fibroblast proliferation
Cellular Component
GO:0005769 early endosome
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0055037 recycling endosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000039321
View Gene Order
ENSBTAG00000018170
Not yet available
Pathways
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.192720
RefSeq NM_018949
HUGO
OMIM
CCDS CCDS11810
HPRD 02938
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca