Version 5.4
Homo sapiens Gene: HINFP
Summary
InnateDB Gene IDBG-74315.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HINFP
Gene Name histone H4 transcription factor
Synonyms HiNF-P; MIZF; ZNF743
Species Homo sapiens
Ensembl Gene ENSG00000172273
Encoded Proteins
IDBP-74317
histone H4 transcription factor
IDBP-591584
histone H4 transcription factor
IDBP-592262
histone H4 transcription factor
IDBP-600928
histone H4 transcription factor
IDBP-601748
histone H4 transcription factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a transcription factor that interacts with methyl-CpG-binding protein-2 (MBD2), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:119121587-119136044
Strand Forward strand
Band q23.3
Transcripts
ENST00000350777 ENSP00000318085
ENST00000527206
ENST00000529354
ENST00000529988 ENSP00000431468
ENST00000531360
ENST00000527354
ENST00000527410 ENSP00000436815
ENST00000530678 ENSP00000433836
ENST00000532312 ENSP00000434574
ENST00000531022
ENST00000529610
ENST00000527755
ENST00000529808
ENST00000532860
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
Experimentally validated
Total 41 [view]
Protein-Protein 41 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0019899 enzyme binding
GO:0042393 histone binding
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000077 DNA damage checkpoint
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0001701 in utero embryonic development
GO:0006281 DNA repair
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0010468 regulation of gene expression
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0045184 establishment of protein localization
GO:0045445 myoblast differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0015030 Cajal body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032119
View Gene Order
ENSBTAG00000015015
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001243259 NM_015517 NM_198971 XM_006718813 XM_006718814
HUGO
OMIM
CCDS CCDS58188 CCDS8414
HPRD 07387
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca