Version 5.4
Homo sapiens Gene: ISCA1
Summary
InnateDB Gene IDBG-74675.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ISCA1
Gene Name iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000135070
Encoded Proteins
IDBP-74679
iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
IDBP-74681
iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
IDBP-74683
iron-sulfur cluster assembly 1 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ISCA1 is a mitochondrial protein involved in the biogenesis and assembly of iron-sulfur clusters, which play a role in electron-transfer reactions (Cozar-Castellano et al., 2004 [PubMed 15262227]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:86264546-86282538
Strand Reverse strand
Band q21.33
Transcripts
ENST00000375991 ENSP00000365159
ENST00000311534 ENSP00000339003
ENST00000326094 ENSP00000365157
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
Biological Process
GO:0016226 iron-sulfur cluster assembly
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000044792
View Gene Order
ENSBTAG00000046526
Not yet available
Cross-References
SwissProt Q9BUE6
TrEMBL B4DJI5 Q5TBE2 Q5TBE9
UniProt Splice Variant
Entrez Gene 81689
UniGene Hs.449291
RefSeq NM_030940
HUGO HGNC:28660
OMIM 611006
CCDS CCDS35056
HPRD
IMGT
EMBL AF284752 AK055643 AK296093 AL137849 AL834356 AY015642 BC002675 BC071621 CH471089
GenPept AAG40950 AAG59854 AAH02675 AAH71621 BAG51546 BAG58847 CAD39021 CAI14925 EAW62713
RNA Seq Atlas 81689

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca