Version 5.4
Homo sapiens Gene: SNX12
Summary
InnateDB Gene IDBG-74774.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX12
Gene Name sorting nexin 12
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000147164
Encoded Proteins
IDBP-74778
sorting nexin 12
IDBP-74780
sorting nexin 12
IDBP-813651
sorting nexin 12
IDBP-813652
sorting nexin 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. A similar protein in mouse may be involved in regulating the neurite outgrowth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome X:71056332-71073426
Strand Reverse strand
Band q13.1
Transcripts
ENST00000374274 ENSP00000363392
ENST00000276105 ENSP00000276105
ENST00000483560
ENST00000490561
ENST00000465030
ENST00000622277 ENSP00000481314
ENST00000622259 ENSP00000483613
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0006886 intracellular protein transport
Cellular Component
GO:0005768 endosome
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000046032
View Gene Order
ENSBTAG00000007871
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001256185 NM_001256188 NM_013346
HUGO
OMIM
CCDS CCDS14405 CCDS59169
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca