Version 5.4
Homo sapiens Gene: PANX3
Summary
InnateDB Gene IDBG-75177.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PANX3
Gene Name pannexin 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000154143
Encoded Proteins
IDBP-75179
pannexin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene belongs to the innexin family. Innexin family members are known to be the structural components of gap junctions. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:124611490-124620356
Strand Forward strand
Band q24.2
Transcripts
ENST00000284288 ENSP00000284288
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0055077 gap junction hemi-channel activity
Biological Process
GO:0006811 ion transport
GO:0007267 cell-cell signaling
GO:0034214 protein hexamerization
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005921 gap junction
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000011118
View Gene Order
ENSBTAG00000009409
Not yet available
Cross-References
SwissProt Q96QZ0
TrEMBL
UniProt Splice Variant
Entrez Gene 116337
UniGene Hs.99235
RefSeq NM_052959
HUGO HGNC:20573
OMIM 608422
CCDS CCDS8447
HPRD
IMGT
EMBL AF406650
GenPept AAK95655
RNA Seq Atlas 116337

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca