Version 5.4
Homo sapiens Protein: PANX3
Summary
InnateDB Protein IDBP-75179.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PANX3
Protein Name pannexin 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000284288
InnateDB Gene IDBG-75177 (PANX3)
Protein Structure
UniProt Annotation
Function Structural component of the gap junctions and the hemichannels.
Subcellular Localization Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000255PROSITE-ProRule:PRU00351}. Cell junction, gap junction.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0055077 gap junction hemi-channel activity
Biological Process
GO:0006811 ion transport
GO:0007267 cell-cell signaling
GO:0034214 protein hexamerization
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005921 gap junction
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000990 Innexin
PFAM PF00876
PRINTS PR01262
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96QZ0
PhosphoSite PhosphoSite-Q96QZ0
TrEMBL
UniProt Splice Variant
Entrez Gene 116337
UniGene Hs.99235
RefSeq NP_443191
HUGO HGNC:20573
OMIM 608422
CCDS CCDS8447
HPRD 16334
IMGT
EMBL AF406650
GenPept AAK95655

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca