Version 5.4
Homo sapiens Gene: ROBO4
Summary
InnateDB Gene IDBG-75299.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ROBO4
Gene Name roundabout, axon guidance receptor, homolog 4 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000154133
Encoded Proteins
IDBP-75301
roundabout homolog 4, magic roundabout (Drosophila)
IDBP-587880
roundabout homolog 4, magic roundabout (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:124883691-124898500
Strand Reverse strand
Band q24.2
Transcripts
ENST00000306534 ENSP00000304945
ENST00000534407
ENST00000533054 ENSP00000437129
ENST00000532216
ENST00000525182
ENST00000532300
ENST00000526899
ENST00000527279
ENST00000529941
ENST00000533337
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0001525 angiogenesis
GO:0030154 cell differentiation
GO:0030334 regulation of cell migration
GO:0030336 negative regulation of cell migration
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032125
View Gene Order
ENSBTAG00000004356
Not yet available
Cross-References
SwissProt
TrEMBL B4DYV8
UniProt Splice Variant
Entrez Gene 54538
UniGene Hs.524121
RefSeq NM_001301088 XM_005271596 XM_005271597 NM_019055
HUGO HGNC:17985
OMIM 607528
CCDS CCDS73409 CCDS8455
HPRD 09604
IMGT
EMBL AK302628 AP003501
GenPept BAG63870
RNA Seq Atlas 54538

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca