Version 5.4
Homo sapiens Gene: ZNRD1
Summary
InnateDB Gene IDBG-75514.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNRD1
Gene Name zinc ribbon domain containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000066379
Encoded Proteins
IDBP-75516
zinc ribbon domain containing 1
IDBP-75518
zinc ribbon domain containing 1
IDBP-75520
zinc ribbon domain containing 1
IDBP-75522
zinc ribbon domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with similarity to the Saccharomyces cerevisiae Rpa12p subunit of RNA polymerase I. Alternate splicing of this gene results in two transcript variants encoding the same protein. Additional splice variants have been described, but their full-length sequences have not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:30058899-30064909
Strand Forward strand
Band p22.1
Transcripts
ENST00000332435 ENSP00000331111
ENST00000359374 ENSP00000352333
ENST00000376785 ENSP00000365981
ENST00000376782 ENSP00000365978
ENST00000471008
ENST00000463141
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 14 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001054 RNA polymerase I activity
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006351 transcription, DNA-templated
GO:0006363 termination of RNA polymerase I transcription
Cellular Component
GO:0005736 DNA-directed RNA polymerase I complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036315
View Gene Order
ENSBTAG00000031792
Not yet available
Pathways
NETPATH
REACTOME
REACT_1074
RNA Polymerase I Transcription Termination pathway
REACT_2204
RNA Polymerase I Chain Elongation pathway
REACT_1913
RNA Polymerase I Promoter Escape pathway
REACT_953
RNA Polymerase I Transcription Initiation pathway
REACT_1309
RNA Polymerase I Transcription pathway
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_1974
RNA Polymerase I Promoter Clearance pathway
REACT_200856
NoRC negatively regulates rRNA expression pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_71
Gene Expression pathway
REACT_200834
Negative epigenetic regulation of rRNA expression pathway
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
hsa03020
RNA polymerase pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001278785 NM_001278786 NM_014596 NM_170783
HUGO
OMIM
CCDS CCDS4670
HPRD 09601
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca