Version 5.4
Bos taurus Gene: ZNRD1
Summary
InnateDB Gene IDBG-635100.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNRD1
Gene Name DNA-directed RNA polymerase I subunit RPA12
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000031792
Encoded Proteins
IDBP-686901
DNA-directed RNA polymerase I subunit RPA12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000066379:
This gene encodes a protein with similarity to the Saccharomyces cerevisiae Rpa12p subunit of RNA polymerase I. Alternate splicing of this gene results in two transcript variants encoding the same protein. Additional splice variants have been described, but their full-length sequences have not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:28714470-28717896
Strand Reverse strand
Band
Transcripts
ENSBTAT00000045075 ENSBTAP00000042491
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001054 RNA polymerase I activity
GO:0003676 nucleic acid binding
GO:0003899 DNA-directed RNA polymerase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006363 termination of RNA polymerase I transcription
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005736 DNA-directed RNA polymerase I complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000066379
View Gene Order
ENSMUSG00000036315
View Gene Order
Pathways
NETPATH
REACTOME
REACT_221445
RNA Polymerase I Transcription Termination pathway
REACT_203707
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_217354
RNA Polymerase I Promoter Escape pathway
REACT_207088
RNA Polymerase I Transcription pathway
REACT_226022
Gene Expression pathway
REACT_225163
RNA Polymerase I Chain Elongation pathway
REACT_208197
RNA Polymerase I Transcription Initiation pathway
REACT_219488
RNA Polymerase I Promoter Clearance pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1074
RNA Polymerase I Transcription Termination pathway
REACT_2204
RNA Polymerase I Chain Elongation pathway
REACT_1913
RNA Polymerase I Promoter Escape pathway
REACT_953
RNA Polymerase I Transcription Initiation pathway
REACT_1309
RNA Polymerase I Transcription pathway
REACT_200857
Epigenetic regulation of gene expression pathway
REACT_1974
RNA Polymerase I Promoter Clearance pathway
REACT_200856
NoRC negatively regulates rRNA expression pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_71
Gene Expression pathway
REACT_200834
Negative epigenetic regulation of rRNA expression pathway
REACT_245058
RNA Polymerase I Transcription pathway
REACT_244415
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_200794
Mus musculus biological processes pathway
REACT_200667
NoRC negatively regulates rRNA expression pathway
REACT_257165
RNA Polymerase I Transcription Termination pathway
REACT_214440
NoRC negatively regulates rRNA expression pathway
REACT_205737
Epigenetic regulation of gene expression pathway
REACT_233572
Gene Expression pathway
REACT_207809
Negative epigenetic regulation of rRNA expression pathway
REACT_232235
RNA Polymerase I Promoter Escape pathway
REACT_240511
RNA Polymerase I Promoter Clearance pathway
REACT_259097
RNA Polymerase I Chain Elongation pathway
REACT_235780
RNA Polymerase I Transcription Initiation pathway
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
hsa03020
RNA polymerase pathway
mmu00240
Pyrimidine metabolism pathway
mmu03020
RNA polymerase pathway
mmu00230
Purine metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q1RMP0
TrEMBL
UniProt Splice Variant
Entrez Gene 535288
UniGene Bt.1771
RefSeq NM_001046400 XM_003583882 XM_003583883 XM_005223668
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114799
GenPept AAI14800
RNA Seq Atlas 100849450 535288

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca