Version 5.4
Homo sapiens Gene: PPP1R11
Summary
InnateDB Gene IDBG-75596.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R11
Gene Name protein phosphatase 1, regulatory (inhibitor) subunit 11
Synonyms HCG-V; HCGV; IPP3; TCTE5; TCTEX5
Species Homo sapiens
Ensembl Gene ENSG00000204619
Encoded Proteins
IDBP-75598
protein phosphatase 1, regulatory (inhibitor) subunit 11
IDBP-75600
protein phosphatase 1, regulatory (inhibitor) subunit 11
IDBP-75602
protein phosphatase 1, regulatory (inhibitor) subunit 11
IDBP-75604
protein phosphatase 1, regulatory (inhibitor) subunit 11
IDBP-75606
protein phosphatase 1, regulatory (inhibitor) subunit 11
IDBP-75608
protein phosphatase 1, regulatory (inhibitor) subunit 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a specific inhibitor of protein phosphatase-1 (PP1) with a differential sensitivity toward the metal-independent and metal-dependent forms of PP1. The gene is located within the major histocompatibility complex class I region on chromosome 6. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:30066709-30070333
Strand Forward strand
Band p22.1
Transcripts
ENST00000376773 ENSP00000365964
ENST00000376772 ENSP00000365963
ENST00000376769 ENSP00000365960
ENST00000376765 ENSP00000365956
ENST00000376763 ENSP00000365954
ENST00000376758 ENSP00000365949
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004864 protein phosphatase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0043086 negative regulation of catalytic activity
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036398
View Gene Order
ENSBTAG00000032247
Not yet available
Pathways
NETPATH
NetPath_24
TSLP pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.82887
RefSeq NM_021959 XM_006715174
HUGO
OMIM
CCDS CCDS4671
HPRD 09449
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca