InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PPP1R11

Summary

InnateDB Protein

IDBP-75600.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PPP1R11

Protein Name

protein phosphatase 1, regulatory (inhibitor) subunit 11

Synonyms

HCG-V; HCGV; IPP3; TCTE5; TCTEX5;

Species

Homo sapiens

Ensembl Protein

ENSP00000365963

InnateDB Gene

IDBG-75596 (PPP1R11)

Protein Structure

UniProt Annotation

Function

Inhibitor of protein phosphatase 1. {ECO:0000269PubMed:9843442}.

Subcellular Localization

Disease Associations

Tissue Specificity

Widely expressed. {ECO:0000269PubMed:8781118}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	5 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004864	protein phosphatase inhibitor activity
GO:0005515	protein binding

Biological Process

GO:0043086

negative regulation of catalytic activity

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR011107 Protein phosphatase inhibitor

PFAM

PF07491

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O60927

PhosphoSite

PhosphoSite-O60927

TrEMBL

Q5SRK2

UniProt Splice Variant

Entrez Gene

6992

UniGene

Hs.82887

RefSeq

NP_068778

HUGO

HGNC:9285

OMIM

606670

CCDS

CCDS4671

HPRD

09449

IMGT

EMBL

AB088087 AB202082 AK313175 AL669914 AL671859 AL845439 BA000025 BC003144 BC102010 BC102011 BC104750 CH471081 U53588 X81003 X89902

GenPept

AAC52082 AAH03144 AAI02011 AAI02012 AAI04751 BAB63334 BAC54919 BAE78601 BAG35992 CAC16919 CAC16920 CAI17578 CAI18177 CAI18539 EAX03253