Version 5.4
Homo sapiens Gene: TRIM31
Summary
InnateDB Gene IDBG-75694.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM31
Gene Name tripartite motif containing 31
Synonyms C6orf13; HCG1; HCGI; RNF
Species Homo sapiens
Ensembl Gene ENSG00000204616
Encoded Proteins
IDBP-75696
tripartite motif containing 31
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to both the cytoplasm and the nucleus. Its function has not been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:30102897-30113106
Strand Reverse strand
Band p22.1
Transcripts
ENST00000376734 ENSP00000365924
ENST00000471695
ENST00000468264
ENST00000484583
ENST00000485864
ENST00000480808
ENST00000493404
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
GO:0032897 negative regulation of viral transcription
GO:0045087 innate immune response
GO:0046597 negative regulation of viral entry into host cell
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity
GO:1902186 regulation of viral release from host cell
Cellular Component
GO:0005622 intracellular
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000058063
View Gene Order
ENSBTAG00000004490
Not yet available
Cross-References
SwissProt Q9BZY9
TrEMBL Q2L6J1
UniProt Splice Variant
Entrez Gene 11074
UniGene Hs.493275 Hs.732862
RefSeq NM_007028 XM_006714977
HUGO HGNC:16289
OMIM 609316
CCDS CCDS34374
HPRD 10281
IMGT
EMBL AB202083 AF230386 AF230387 AK222729 AK290270 AL669914 AL671859 BC016866 BC017017 BT006675 BX005441 BX088647 BX322644 BX897730 CR753815 Y07828
GenPept AAG50165 AAG50166 AAH16866 AAH17017 AAP35321 BAD96449 BAE78603 BAF82959 CAA69165 CAI17583 CAI18183 CAI18447 CAM26290 CAP58476
RNA Seq Atlas 11074

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca