Version 5.4
Homo sapiens Gene: NCAPD3
Summary
InnateDB Gene IDBG-76443.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NCAPD3
Gene Name non-SMC condensin II complex, subunit D3
Synonyms CAP-D3; CAPD3; hCAP-D3; hcp-6; hHCP-6
Species Homo sapiens
Ensembl Gene ENSG00000151503
Encoded Proteins
IDBP-586337
non-SMC condensin II complex, subunit D3
IDBP-597911
non-SMC condensin II complex, subunit D3
IDBP-585775
non-SMC condensin II complex, subunit D3
IDBP-598390
non-SMC condensin II complex, subunit D3
IDBP-591761
non-SMC condensin II complex, subunit D3
IDBP-599877
non-SMC condensin II complex, subunit D3
IDBP-600629
non-SMC condensin II complex, subunit D3
IDBP-590822
non-SMC condensin II complex, subunit D3
IDBP-595598
non-SMC condensin II complex, subunit D3
IDBP-603722
non-SMC condensin II complex, subunit D3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:134150119-134225454
Strand Reverse strand
Band q25
Transcripts
ENST00000526787
ENST00000534532 ENSP00000434168
ENST00000534548 ENSP00000433681
ENST00000525964 ENSP00000431612
ENST00000525432
ENST00000527944 ENSP00000432532
ENST00000530396 ENSP00000435173
ENST00000534290
ENST00000533155 ENSP00000431413
ENST00000528065
ENST00000525485 ENSP00000436037
ENST00000534227 ENSP00000431436
ENST00000526422 ENSP00000435586
ENST00000532445 ENSP00000435655
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0035064 methylated histone binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007076 mitotic chromosome condensation
Cellular Component
GO:0000793 condensed chromosome
GO:0000799 nuclear condensin complex
GO:0005654 nucleoplasm
GO:0016020 membrane
GO:0031618 nuclear centromeric heterochromatin
GO:0042585 germinal vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035024
View Gene Order
ENSBTAG00000002260
Not yet available
Pathways
NETPATH
REACTOME
REACT_172744
Condensation of Prophase Chromosomes pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_765
Mitotic Prophase pathway
REACT_152
Cell Cycle, Mitotic pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.438550
RefSeq NM_015261
HUGO
OMIM
CCDS CCDS31723
HPRD 11062
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca