InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NCAPD3

Summary

InnateDB Protein

IDBP-597911.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NCAPD3

Protein Name

non-SMC condensin II complex, subunit D3

Synonyms

CAP-D3; CAPD3; hCAP-D3; hcp-6; hHCP-6;

Species

Homo sapiens

Ensembl Protein

ENSP00000433681

InnateDB Gene

IDBG-76443 (NCAPD3)

Protein Structure

UniProt Annotation

Function

Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. {ECO:0000269PubMed:14532007}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:14532007}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0035064	methylated histone binding

Biological Process

GO:0000278	mitotic cell cycle
GO:0007076	mitotic chromosome condensation

Cellular Component

GO:0000793	condensed chromosome
GO:0000799	nuclear condensin complex
GO:0005654	nucleoplasm
GO:0016020	membrane
GO:0031618	nuclear centromeric heterochromatin
GO:0042585	germinal vesicle