Version 5.4
Homo sapiens Gene: HKDC1
Summary
InnateDB Gene IDBG-76707.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HKDC1
Gene Name hexokinase domain containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000156510
Encoded Proteins
IDBP-76709
hexokinase domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 10:69220303-69267559
Strand Forward strand
Band q22.1
Transcripts
ENST00000354624 ENSP00000346643
ENST00000488706
ENST00000470920
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004340 glucokinase activity
GO:0005524 ATP binding
GO:0008865 fructokinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0019158 mannokinase activity
Biological Process
GO:0001678 cellular glucose homeostasis
GO:0005975 carbohydrate metabolic process
GO:0006096 glycolytic process
GO:0019318 hexose metabolic process
GO:0046835 carbohydrate phosphorylation
GO:0051156 glucose 6-phosphate metabolic process
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020080
View Gene Order
ENSBTAG00000033398
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00052
Galactose metabolism pathway
hsa00010
Glycolysis / Gluconeogenesis pathway
hsa00520
Amino sugar and nucleotide sugar metabolism pathway
hsa04910
Insulin signaling pathway pathway
hsa00500
Starch and sucrose metabolism pathway
hsa00051
Fructose and mannose metabolism pathway
hsa04930
Type II diabetes mellitus pathway
hsa04973
Carbohydrate digestion and absorption pathway
hsa00524
Butirosin and neomycin biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q2TB90
TrEMBL
UniProt Splice Variant
Entrez Gene 80201
UniGene Hs.522988
RefSeq NM_025130
HUGO HGNC:23302
OMIM
CCDS CCDS7288
HPRD
IMGT
EMBL AK026414 AL596223 BC012337 BC021278 BC110504 BC110505 BX538078
GenPept AAH12337 AAH21278 AAI10505 AAI10506 BAB15478 CAD98002 CAH71500
RNA Seq Atlas 80201

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca