Version 5.4
Homo sapiens Protein: HKDC1
Summary
InnateDB Protein IDBP-76709.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HKDC1
Protein Name hexokinase domain containing 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000346643
InnateDB Gene IDBG-76707 (HKDC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004340 glucokinase activity
GO:0005524 ATP binding
GO:0008865 fructokinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0019158 mannokinase activity
Biological Process
GO:0001678 cellular glucose homeostasis
GO:0005975 carbohydrate metabolic process
GO:0006096 glycolytic process
GO:0019318 hexose metabolic process
GO:0046835 carbohydrate phosphorylation
GO:0051156 glucose 6-phosphate metabolic process
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR001312 Hexokinase
IPR022672 Hexokinase, N-terminal
IPR022673 Hexokinase, C-terminal
PFAM PF00349
PF03727
PRINTS PR00475
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q2TB90
PhosphoSite PhosphoSite-Q2TB90
TrEMBL
UniProt Splice Variant
Entrez Gene 80201
UniGene Hs.522988
RefSeq NP_079406
HUGO HGNC:23302
OMIM
CCDS CCDS7288
HPRD 08006
IMGT
EMBL AK026414 AL596223 BC012337 BC021278 BC110504 BC110505 BX538078
GenPept AAH12337 AAH21278 AAI10505 AAI10506 BAB15478 CAD98002 CAH71500

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca