Version 5.4
Homo sapiens Gene: BARX1
Summary
InnateDB Gene IDBG-76800.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BARX1
Gene Name BARX homeobox 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000131668
Encoded Proteins
IDBP-76804
BARX homeobox 1
IDBP-295691
BARX homeobox 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the Bar subclass of homeobox transcription factors. Studies of the mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:93951622-93955372
Strand Reverse strand
Band q22.32
Transcripts
ENST00000253968 ENSP00000253968
ENST00000401724 ENSP00000385613
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000976 transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007267 cell-cell signaling
GO:0009888 tissue development
GO:0009952 anterior/posterior pattern specification
GO:0030178 negative regulation of Wnt signaling pathway
GO:0030855 epithelial cell differentiation
GO:0048513 organ development
GO:0048536 spleen development
GO:0048856 anatomical structure development
GO:0055123 digestive system development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021381
View Gene Order
ENSBTAG00000004468
Not yet available
Cross-References
SwissProt Q9HBU1
TrEMBL
UniProt Splice Variant
Entrez Gene 56033
UniGene Hs.605207
RefSeq NM_021570
HUGO HGNC:955
OMIM 603260
CCDS CCDS35070
HPRD
IMGT
EMBL AF213356 AL357073 BC009458 BC064363 CH471089
GenPept AAG23738 AAH09458 AAH64363 CAQ06883 CAQ06884 EAW62873
RNA Seq Atlas 56033

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca